Researcher in Immunogenomics - Hiring in process/Finished, not possible to apply

The Department of Medical Sciences is a large clinical institution with more than 250 employees and over 900 additional coworkers connected via the Uppsala University Hospital. The Department of Medical Sciences has a broad research profile with strong research groups in a number of different areas. The research carried out at the department is performed in close connection with the clinical activities at the Uppsala University Hospital, which includes both basic studies on the causes of a variety of illnesses and the development and evaluation of improved diagnostics and new treatment methods. More information about the Department of Medical Sciences can be found at www.medsci.uu.se.

The Rheumatology research group focusing on systemic autoimmunity at the Department of Medical Sciences looks for a researcher to join the group for a period of 12 months. The research group studies inflammatory rheumatic diseases including Systemic Lupus Erythematosus (SLE), Sjögren’s disease and ANCA-vasculitis. We study the genome and different cells of the immune system in patients and healthy individuals, aiming at clarifying the mechanisms behind disease in order to develop new and effective treatments. We collaborate with national and international networks of clinicians and researchers and also with the pharmaceutical industry. For more information, see www.uu.se/en/department/medical-sciences/research/research-groups/rheumatology

Job description: 

Our research group has contributed to the discovery of >25 risk loci associated with development of SLE. Some of these single nucleotide polymorphisms (SNPs) are associated with specific manifestations of the disease such as cardiovascular disease manifestations. Recently, we focus on investigating the effect of cumulative genetics on disease mechanisms and phenotype. In this project, we will also investigate the impact of immunogenetics on disease mechanisms and phenotype in the general population. To do this we will analyze large available datasets and our own SLE cohort with extensive genetic, epigenetic and clinical data.

We expect our new colleague to independently plan and perform analysis in collaboration with the rest of the team. Presentation of data and writing manuscripts will also be of great importance.

Required qualifications: 

PhD in medicine, biology, bioinformatics or genetics Expert knowledge of SLE genetics Several years of experience in genetic research both in Sweden and internationally Expert knowledge of genetic- and statistical analysis including analysis of GWAS-data Experience of genetic risk prediction model development Ability to interpret omics data in a biological context Expert knowledge and experience of large-scale OMICs data analysis Experience of student supervision Ability to work independently Interest to share knowledge with colleagues Expert knowledge of written and spoken English Personal qualities will be an important selection criterion in particular ability to work together with other researchers, physicians and bioinformaticians

Additional qualifications:

Postdoc in i.e. human genetics

Application:

The application should contain a letter describing the applicant’s research interests and relevant qualifications. The application should also include a CV, a list of publications, copies of diplomas and certificates of higher academic degrees as well as contact details (name, e-mail, phone number) of two referees. Specify earliest possible start date.

This is a temporary position, 12 months. The scope of employment is 100%. Starting date is September 2024 or otherwise agreed. Placement: Uppsala

For further information about the position, please contact: MD, Associate professor, Dag Leonard, dag.leonard@medsci.uu.se

 In this recruitment we have replaced the cover letter with questions that you are asked to answer when making your application. The answers will be used as a part of the selection process.

Please submit your application by June 12, 2024, UFV-PA 2024/1978.

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