PhD student in Chemistry – Specializing in Molecular Biomimetics - Hiring in process/Finished, not possible to apply

The student will be part of the bioinorganic chemistry group within the molecular biomimetics program. The program, which is highly recognized internationally, is part of the Department of Chemistry – Ångström at Uppsala University. The group is situated in a modern building at the Ångström Laboratory. The research at the department spans from organic, inorganic and physical chemistry to biochemistry and biophysics, and strong cross-disciplinary collaborations are characteristic for the program.

More information is available on our website.

Project description 
The research project involves biochemistry, biophysics and bioinorganic chemistry. The hydrogenase enzymes are central to hydrogen metabolism, as they catalyze the formation and oxidation of H2 gas. This chemistry is enabled by a biologically unique organometallic cofactor. An increased understanding of these enzymes is critical for our understanding of the biological H2 cycle. Due to their remarkable efficiencies they are also intensively studied in (bio)technological applications. The project follows one of the major project lines in the group, which focuses on the biochemical characterization of novel examples of this diverse enzyme family. In parallel, it also involves the development of new methods for studying their mechanism using advanced, time-resolved, spectroscopic techniques.

Read more about our benefits and what it is like to work at Uppsala University

Duties
The applicant will work in an interdisciplinary project that involves biochemistry, molecular biology and biophysics. The primary role of the PhD student in the project will deal with the isolation and characterization of novel [FeFe] hydrogenases of potential biotechnological or medical relevance. Selected enzymes will be characterized in depth utilizing a combination of electrochemistry and time-resolved spectroscopy (transient absorbance and IR spectroscopy), with a focus on determining reaction mechanisms. The work will be performed by the PhD student in collaboration with theoreticians, spectroscopists and synthetic chemists at Uppsala University and abroad.

The main duties of doctoral students are to devote themselves to their research studies which includes participating in research projects mentioned above and third cycle courses. The work duties can also include teaching and other departmental duties (no more than 20%).

Eligibility requirements
A person meets the general admission requirements for third-cycle courses and study programmes if he or she:

• has been awarded a second-cycle qualification, or
• has satisfied the requirements for courses comprising at least 240 credits of which at least 60 credits were awarded in the second cycle, or has acquired essentially equivalent knowledge in some other way in Sweden or abroad.

Requirements

• Degree or equivalent as above in chemistry, biochemistry, biophysics or molecular biology.
• Very good oral and written proficiency in English.
• The ability of the PhD student to be innovative and not afraid to go outside traditional discipline.

Consideration will also be given to good collaborative skills, drive and independence, and how the applicant’s experience and skills complement and strengthen ongoing research within the department, and how they stand to contribute to its future development.

Additional qualifications

• Advanced knowledge and/or practical experience in biochemistry, biophysics and/or (bio)inorganic chemistry is desirable.
• Prior experience in working with metalloenzymes will be beneficial.

Rules governing PhD students are set out in the Higher Education Ordinance chapter 5, §§ 1-7 and in Uppsala University's rules and guidelines.

About the employment
The employment is a temporary position according to the Higher Education Ordinance chapter 5 § 7. Scope of employment 100 %. Starting date 2022-03-01 or as agreed. Placement: Uppsala.

For further information about the position, please contact: Dr. Gustav Berggren, gustav.berggren@kemi.uu.se.

Please submit your application by 31 January 2022, UFV-PA 2021/4825.

Are you considering moving to Sweden to work at Uppsala University? Find out more about what it´s like to work and live in Sweden.