Uppsala University, Department of Immunology, Genetics and Pathology

The Department of Immunology, Genetics and Pathology at Uppsala University (www.igp.uu.se) has a broad research profile with strong research groups focused on cancer, autoimmune and genetic diseases. A fundamental idea at the department is to stimulate translational research and thereby closer interactions between medical research and health care. Research is presently conducted in the following areas: medical and clinical genetics, clinical immunology, pathology, neuro-oncology, vascular biology, radiation science and molecular tools. Department activities are also integrated with the units for Oncology, Clinical Genetics, Clinical Immunology, Clinical Pathology, and Hospital Physics at Akademiska sjukhuset, Uppsala. The department has teaching assignments in several education programmes, including Master Programmes, at the Faculty of Medicine, and in a number of educations at the Disciplinary Domain of Science and Technology. The department has a yearly turnover of around SEK 400 million, out of which more than half is made up of external funding. The staff amounts to approximately 340 employees, out of which 100 are PhD-students, and there are in total more than 600 affiliated people.

Project description: A PhD student position is available for highly motivated individuals with an interest in translational genomics to join the laboratory of Associate Prof Marcel den Hoed at Uppsala University, Department of Immunology, Genetics and Pathology. Research in the lab focuses on translating results from genome-wide association studies for cardiometabolic diseases into improved functional understanding. The goal of the project is to develop and validate a zebrafish model system that is suitable for systematic image and CRISPR-Cas9-based characterisation of candidate genes and drugs for liver fibrosis, and to use this model system - and model systems we already developed and validated - to characterise candidate genes with an anticipated role in NAFLD and/or coronary artery disease.

Further information on the activity of the research group can be accessed at https://igp.uu.se/research/genetics_genomics/marcel-den-hoed/

The successful candidate will devote most of the time towards his/her research level education. Other service activities within the department, e.g. education and administrative work can be included within the framework of the employment (maximum 20%). The position will be extended with the time devoted to teaching to allow four years of full time graduate studies.

Qualifications: A successful candidate should be a highly motivated, organised, reliable team player that can also work independently. The applicant should have an MSc degree in a relevant area (e.g. Biomedicine, Molecular Medicine, Medicine, Molecular Cell Biology). A basic knowledge of, and skills in molecular biology are required. Strong merits would be experience in laboratory practice, CRISPR-Cas9 genome editing, zebrafish husbandry, fluorescence or confocal microscopy, epidemiology, data management, biostatistics and/or image-based analyses. Excellent skills in oral and written English are essential.

Information about education at the postgraduate level, admission requirements and admission decisions can be found at http://www2.medfarm.uu.se/utbildning/forskarniva/vill_du_borja/

Selection of applicants will be done by the future tutor for the selected student, in consultation with the postgraduate study group of the Department. The Postgraduate Programmes Committee at the Disciplinary Domain of Medicine will formally approve the student's admission.

Rules governing PhD students are set out in the Higher Education Ordinance chapter 5, §§ 1-7 and in Uppsala University's rules and guidelines http://regler.uu.se/?languageId=1.

Salary: According to local agreement for PhD students.

Starting date: According to the agreement.

Type of employment: Temporary position according to the Higher Education Ordinance chapter 5 § 7.

Scope of employment: 100 %

For further information about the position please contact: Researcher Marcel den Hoed, marcel.den_hoed@igp.uu.se. 

Please submit your application by 15 April 2020, UFV-PA 2020/611.

Are you considering moving to Sweden to work at Uppsala University? If so, you will find a lot of information about working and living in Sweden at www.uu.se/joinus. You are also welcome to contact International Faculty and Staff Services at ifss@uadm.uu.se.

Type of employment Temporary position
Contract type Full time
First day of employment According to the agreement.
Salary Fixed salary
Number of positions 1
Full-time equivalent 100 %
City Uppsala
County Uppsala län
Country Sweden
Reference number UFV-PA 2020/611
Union representative
  • Saco-rådet, saco@uadm.uu.se
  • ST/TCO, tco@fackorg.uu.se
  • Seko Universitetsklubben, seko@uadm.uu.se
Published 30.Mar.2020
Last application date 15.Apr.2020 11:59 PM CEST

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