Postdoctoral position in pancreatic neuroendocrine (pan-NET) tumor biology

The Department of Surgical Sciences (IKV) is part of the Disciplinary Domain of Medicine and Pharmacy. IKV has about 160 employees and 230 registered doctoral (third cycle) students, the majority of which are clinically active doctors and nurses. The yearly turnover is SEK 152 million. Research is conducted at the department, as well as teaching in the first, second and third cycles. Teaching is, among other areas, conducted within the education programmes for doctors, nurses and specialty nurses.

Research is conducted in research groups organised according to surgical specialties and closely aligned subject areas, such as anaesthesia and intensive care and radiology. A great deal of research is conducted in cooperation between separate research groups within IKV and other departments at Uppsala University, as well as other universities in Sweden and the rest of the world. Many of the department's employees have combined positions at the University Hospital.

The project will take place at the Rudbeck laboratory- a research facility within the Disciplinary domain of Medicine and Pharmacy at Uppsala University - which aims to facilitate translational research approaches.

The work tasks will be to

1)  Overall:

• Utilizing biobank-derived tissues and blood from pan-NET patients, combined with multi-omic approaches, to uncover fundamental mechanisms predictive of treatment response, prognosis, and potential new therapeutic targets.
• Work well as part of a team, as well as independently.

2)  Data management and statistical analysis:

• Perform preparation of tissues and blood and apply cutting edge technologies in multi-omics.
• Apply advanced bioinformatic analyses using state-of-the-art tools and methodologies.
• Conduct rigorous statistical analyses in alignment with predefined statistical analysis plans and in connection with clinical data.

3)  Presentation of results:

• Interpret new results in the context of the existing scientific knowledge.
• Communicate clearly and professionally in oral and written English in different situations, for example, within interdisciplinary meetings and collaborations, when drafting and revising articles to be published in peer-reviewed journals, and when presenting new insights at (inter)national conferences.

Requirements

PhD degree in Medicine with emphasis on bioinformatics and multiomics, or a foreign degree equivalent to a PhD degree involving the above. The degree needs to be obtained by the time of the decision of employment. Those who have obtained a PhD degree three years prior to the application deadline are primarily considered for the employment. The starting point of the three-year frame period is the application deadline. Due to special circumstances, the degree may have been obtained earlier. The three-year period can be extended due to circumstances such as sick leave, parental leave, duties in labour unions, etc.

Furthermore, the candidate is required to have:

• - A strong interest and background in molecular medicine.
• - Extensive hands-on laboratory experience, with proficiency in molecular biology, cell-based and functional assays, and strong skills in data analysis and experimental troubleshooting.
• - Advanced knowledge in bioinformatics and programming (R and Python).
• - Extensive knowledge in gene array technologies, next-generation sequencing (including whole-genome, bulk RNA, and single-cell RNA sequencing), third-generation long-read sequencing, and in vivo animal models.
• - Experience in independently programming statistical analyses of a combination of bioinformatic data and clinical data.

We are looking for a cooperative person that works well with others as well as independently. You have strong organizational skills and the ability to prioritize your tasks. Furthermore, you are detail-oriented and have a professional approach. Excellent scientific writing ability in English and excellent oral and written communication in English are required.

Additional qualifications

• - Prior experience of performing advanced bioinformatics.
• - Experience of lifestyle, socioeconomic position and/or cancer related
• - Previous outstanding academic
• - Laboratory Animal Science Certification (FELASA A, B, C & D)

Application should include:

• A CV or resume (max 2 A4 pages in English)
• A cover letter in which you present your research interests and experience, and explain why you are interested in and suitable for this position (max 1 A4 page in English)
• A list of publications
• A copy of your PhD certificate if available
• Contact details (name, email, and phone number) for two professional references

About the employment

The employment is a temporary position of 2 years according to central collective agreement, with potential for extension to a third year. Scope of employment 100 %. Starting date 251101 or as agreed. Placement: Uppsala

For further information about the position, please contact: Peter Stålberg, professor. peter.stalberg@uu.se

For questions regarding the employment process, please contact HR representative Louise Walther, louise.walther@uu.se

Please submit your application by 17 oktober UFV-PA 2025/2955