Researcher

The Department of Immunology, Genetics and Pathology at Uppsala University has a broad research profile with strong research groups focusing on cancer, genetic and autoimmune diseases. A fundamental idea at the department is to stimulate translational research and thereby promote closer interactions between medical research and health care. Research is presently organized in six research programs: Cancer Precision Medicine, Cancer Immunotherapy, Genomics and Neurobiology, Molecular Tools and Functional Genomics, Neuro-Oncology and Neurodegeneration and Vascular Biology. Departmental activities are also integrated with the units for Oncology, Clinical Genetics, Clinical Immunology, Clinical Pathology, and Hospital Physics at Uppsala University Hospital. The department has teaching assignments in several education programs, including Master Programs, at the Faculty of Medicine. The department has a yearly turnover of around SEK 550 million, out of which about two thirds derive from external funding. IGP has approximately 400 employees, out of which 100 are PhD-students, and there are in total more than 850 affiliated staff members. More information about the department's activities can be found here: www.uu.se/en/staff/department/immunology-genetics-and-pathology

Duties
This translational project aims to improve understanding of how tumor microenvironment in colorectal cancer (CRC) is affecting prognosis and response to treatment. The study uses state-of-the-art methodologies for multiplexed in situ cancer profiling, combined with project-specific methods for quantifications of fibroblast and vessel characteristics. Studies are performed using a set of clinically well-annotated large CRC collections. The project is a collaboration between the groups of Prof. Tobias Sjöblom, Uppsala University, Prof. Arne Östman, Karolinska Institutet and Prof. Pia Österlund, Karolinska Institutet/Helsinki University.

Requirements
The candidate should have a PhD degree and at least 4 years of experience of post-doctoral work in a relevant area. Documented expertise in multiplex staining and associated digital image analysis is required.

Additional qualifications
Earlier experience of quantitative profiling of tumor microenvironment is considered as an additional merit.

About the employment
The employment is a temporary position, 11 months. Scope of employment 100 %. Starting date as agreed. Placement: Uppsala

For further information about the position, please contact: Tobias Sjöblom, tobias.sjoblom@igp.uu.se

Please submit your application by 10 July 2025, UFV-PA 2025/2208.

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