Postdoctoral position in microalgae precision phenotyping

Uppsala University invites applications for a two-year postdoctoral position in single-cell microalgae phenotyping and lipidomics. This project offers a unique opportunity to work at the intersection of biotechnology and environmental science, leveraging cutting-edge microfluidics, high-content imaging, and lipidomics to revolutionize microalgae-based biofuel production and ecosystem restoration. Please note that the project will entail extended stays at both Uppsala University, Sweden and the Danish Technical University (DTU) in Copenhagen, Denmark.

Project overview

Microalgae are essential for bioenergy, food, and climate resilience, yet their phenotypic characterization remains a challenge. This project aims to develop an advanced phenotyping platform that integrates microfluidics and high-content imaging to identify microalgae with enhanced lipid production and thermal tolerance. By selecting and evolving microalgae with desirable traits, this research could transform the economic viability of microalgal bioproduction through assisted evolution strategies. The selected candidate will contribute to groundbreaking work with real-world applications in sustainable biotechnology. This interdisciplinary project also includes collaboration with international experts in lipidomics.

Duties

Develop and optimize microfluidic platforms for single-cell microalgae phenotyping. Conduct high-content imaging (fluorescence, quantitative phase imaging, PAM microscopy) to analyze single-cell traits. Perform single-cell lipidomics to establish correlations between phenotypic traits and lipid content. Integrate automation and data processing pipelines for high-throughput microalgae selection. Conduct experiments on microalgae. Analyze experimental data and write scientific publications and presentations. Collaborate with researchers at Uppsala University and DTU.

Required qualifications

PhD in (bio)engineering, microbiology, biophysics or related fields. The degree needs to be obtained by the time of the decision of employment. Priority will be given to applicants who have completed their degree no more than three years before the deadline for applications.  Due to special circumstances, the degree may have been obtained earlier. The three-year period can be extended due to circumstances such as sick leave, parental leave, duties in labour unions, etc. Expertise in microfluidics, microalgae cultivation, high-content imaging, or lipidomics Experience with fluorescence microscopy, PAM microscopy, or single-cell imaging techniques. Excellent communication skills in English (both written and spoken). Strong analytical skills, independence, and ability to work in collaborative environments internationally.

Additional qualifications

• Programming skills (e.g., Python, MATLAB) for data analysis are a strong plus.

About the employment
The employment is a temporary position of 2 years according to central collective agreement. Full time position. Starting date 2025-06-01 or as agreed. Placement: The candidate will be hired at Uppsala University but split their time between two leading research institutions:

DTU Bioengineering (Copenhagen, Denmark), year 1 – Method development Uppsala University, Dept. of Organismal Biology (Sweden), year 2 –Experimental work

Application process

A CV detailing relevant research experience and publications. A motivation letter (max. 2 pages) explaining research interests and suitability for the position. Contact details for two referees.

For further information about the position, please contact: Dr. Lars Behrendt +46 763151045, lars.behrendt@scilifelab.uu.se.

Please submit your application by the 1st of May 2025, UFV-PA 2025/939.

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