PhD student in cancer precision medicine

PhD student in cancer precision medicine

The Department of Immunology, Genetics and Pathology at Uppsala University has a broad research profile with strong research groups focused on cancer, autoimmune and genetic diseases. A fundamental idea at the department is to stimulate translational research and thereby closer interactions between medical research and health care. Research is presently conducted in the following areas: medical and clinical genetics, clinical immunology, pathology, neuro biology, neuro-oncology, vascular biology, radiation science and molecular tools. Department activities are also integrated with the units for Oncology, Clinical Genetics, Clinical Immunology, Clinical Pathology, and Hospital Physics at Akademiska sjukhuset, Uppsala. The department has teaching assignments in several education programmes, including Master Programmes, at the Faculty of Medicine, and at the Disciplinary Domain of Science and Technology. The department has a yearly turnover of around SEK 500 million, out of which more than half is made up of external funding. The staff amounts to approximately 345 employees, out of which 100 are PhD-students, and there are in total more than 700 affiliated people. Feel free to read more about the department's activities here: https://www.uu.se/en/department/immunology-genetics-and-pathology

Duties
You will develop and characterize cell models for novel treatment targets that have undergone loss of heterozygosity in colorectal cancer. You will engineer variants in human cancer cells using CRISPR-SELECT and other advanced genome editing methods. You will characterize these cell models with respect to phenotypes and response to different commonly used cancer therapies.  

Requirements
Master’s degree in the life science area. Documented experience from laborative work with human cell culture.

Additional qualifications
Documented experience from CRISPR-based genome editing

You can find information about education at postgraduate level, eligibility requirements and admission regulations at https://www.uu.se/en/disciplinary-domain/medicine-and-pharmacy/study/doctoral-studies   

Selection of applicants is made by the supervisor in consultation with the department's postgraduate education group. The doctoral education committee in the discipline of medicine-pharmacy accepts the doctoral student.  Salary placement takes place according to local guidelines at Uppsala University.

Rules governing PhD students are set out in the Higher Education Ordinance chapter 5, §§ 1-7 and in Uppsala University's rules and guidelines.

About the employment
The employment is a temporary position according to the Higher Education Ordinance chapter 5 § 7. Scope of employment 100 %. Starting date as agreed. Placement: Uppsala

For further information about the position, please contact: Tobias Sjöblom, 018-4715036, tobias.sjoblom@igp.uu.se

Please submit your application by 10 April 2025, UFV-PA 2025/382.

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