Uppsala University, Department of Immunology, Genetics and Pathology

The Department of Immunology, Genetics and Pathology at Uppsala University has a broad research profile with strong research groups focusing on cancer, genetic and autoimmune diseases. A fundamental idea at the department is to stimulate translational research and thereby promote closer interactions between medical research and health care. Research is presently organized in six research programs: Cancer Precision Medicine, Cancer Immunotherapy, Genomics and Neurobiology, Molecular Tools and Functional Genomics, Neuro-Oncology and Neurodegeneration and Vascular Biology. Departmental activities are also integrated with the units for Oncology, Clinical Genetics, Clinical Immunology, Clinical Pathology, and Hospital Physics at Uppsala University Hospital. The department has teaching assignments in several education programs, including Master Programs, at the Faculty of Medicine, and the Faculty of Science and Technology. The department has a yearly turnover of around SEK 550 million, out of which about two thirds derive from external funding. IGP has approximately 400 employees, out of which 100 are PhD-students, and there are in total more than 850 affiliated staff members. More information about the department's activities can be found here: www.uu.se/en/staff/department/immunology-genetics-and-pathology

Duties  
The position focuses on leveraging zebrafish as a model organism to develop and optimize advanced genetic tools, with significant therapeutic and industrial applications. 
Key responsibilities include: 

1- Pipeline development and innovation: 
-Design and establish zebrafish models  for the development of advanced genetic tools for high-throughput screening. 
-Implement in vitro and in vivo mutagenesis strategies and fluorescence-based screening workflows using CRISPR/Cas9, Phi-C31 integrase, and FACS.
-Apply next-generation sequencing techniques to screening workflows.

2- Commercialization and strategic growth: 
-Develop patentable genetic tools and optimization pipelines with high commercial potential. 
-Collaborate with internal and external stakeholders to secure partnerships and promote the application of developed technologies in academia and industry.

3- Project leadership and delivery: 
-Manage project timelines, documentation, and milestones, ensuring timely delivery of results. 
-Coordinate interdisciplinary teams and align project outputs with strategic goals, including publications, patents, and market-ready tools. 

4- Communication: 
-Represent the project at conferences and industry events, fostering strategic partnerships. 
-Contribute to research grant writing and business proposals to support project sustainability and growth 

Requirements
Required:
- Ph.D. in Molecular Biology, Genetics, Bioengineering, or a related field.
- Proven experience in zebrafish research, including transgenesis and CRISPR/Cas9-based genome editing.
- Demonstrated expertise in high-throughput genetic or molecular screening pipelines, including mutagenesis 
and FACS.
- Strong project management skills with a track record of delivering complex projects on time.
- Excellent communication skills and experience in stakeholder engagement.

Additional qualifications
-Experience in patenting and commercialization of research outputs.
-Proficiency in identifying market opportunities and building strategic partnerships.
-Knowledge of bioinformatics tools for library design and data analysis.
-Proven ability to lead interdisciplinary teams and collaborate across academia and industry.
-Background in business development or strategic planning in a research or biotech setting

About the employment
The employment is a temporary position, 12 months. Scope of employment 100 %. Starting date as agreed. Placement: Uppsala

For further information about the position, please contact: Thomas Juan, thomas.juan@igp.uu.se

Please submit your application by 13th December 2024, UFV-PA 2024/4093.

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Type of employment Special fixed-term employment
Contract type Full time
First day of employment snarast
Salary Individual salary
Number of positions 1
Full-time equivalent 100%
City Uppsala
County Uppsala län
Country Sweden
Reference number UFV-PA 2024/4093
Union representative
  • Seko Universitetsklubben, seko@uadm.uu.se
  • ST/TCO, tco@fackorg.uu.se
  • Saco-rådet, saco@uadm.uu.se
Published 28.Nov.2024
Last application date 13.Dec.2024 11:59 PM CET

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