This advert is not available!
Are you interested in working with RNA cryoEM, with the support of competent and friendly colleagues in an international environment? Are you looking for an employer that invests in sustainable employeeship and offers safe, favourable working conditions? We welcome you to apply for a Research assistant position at Uppsala University.
The Department of Cell and Molecular Biology is divided into seven research programs that focus on different areas within cell and molecular biology: computational biology and bioinformatics, microbiology, molecular biology, molecular biophysics, molecular evolution, molecular systems biology and structural biology. The scientific basis of what we do is in biology, but our research overlaps with other fields such as medicine, computer science, mathematics, chemistry, engineering and physics. The department has over 200 employees with around 60 PhD students. Please read more about the organization's work at https://icm.uu.se.
The research assistant will work in Marco Marcia’s research group. Marco Marcia leads a research group in structural and cell biology and RNA biochemistry. The group works with RNA cryoEM and X-ray crystallography, coupled to RNA chemical probing, mutagenesis, cellular functional assays, and RNA-protein interaction techniques. These are used to understand structure-function relationships in large catalytic and regulatory non-coding RNAs involved in bacterial and fungal infections, cancer and neurodevelopmental disorders. The employee will work in an international and dynamic environment with great opportunities to learn new techniques. We will have a well-equipped lab, in house access to a Glacios cryoEM microscope, and access to national SciLifeLab facilities in structural biology, proteomics, genomics, chemical biology, genetic engineering, and imaging in Uppsala, Stockholm, and Gothenburg.
Duties
We are looking for a research assistant with excellent credentials and strong motivation to identify and solve scientific problems. The employee will work in a project that aims to understand structural and mechanistic aspects of how bacterial and fungal self-splicing ribozymes acquire their catalytic 3D structures. Tasks include general RNA-based molecular biology techniques (cloning, mutagenesis, in vitro transcription), RNA purification, biochemical and biophysical characterization (electrophoresis, MALLS, mass photometry), and RNA structural biology (crystallography, cryoEM).
The research assistant will work closely with a doctoral student and other researchers with partly complementary competences, but is expected to run their own project independently. A strong track record with documented laboratory skills, motivation and good collaboration skills is a prerequisite for the position.
Requirements
The candidate should have or be about to obtain a PhD degree in molecular biology, biochemistry, or analogous fields.
Additional qualifications
The application must contain:
About the employment
The employment is a temporary position, 12 months. Scope of employment 100%. Starting date November 1st 2024 or as agreed. Placement: Uppsala.
For further information about the position, please contact: Marco Marcia, 0033-(0)476207759, marco.marcia@icm.uu.se
Please submit your application by 17 May 2024, UFV-PA 2024/1546.
Are you considering moving to Sweden to work at Uppsala University? Find out more about what it´s like to work and live in Sweden.
Type of employment | Temporary position |
---|---|
Contract type | Full time |
First day of employment | November 1st 2024 or as agreed. |
Salary | Individual salary |
Number of positions | 1 |
Full-time equivalent | 100% |
City | Uppsala |
County | Uppsala län |
Country | Sweden |
Reference number | UFV-PA 2024/1546 |
Union representative |
|
Published | 03.May.2024 |
Last application date | 17.May.2024 11:59 PM CEST |