Uppsala University, Department of Cell and Molecular Biology

The Department of Cell and Molecular Biology is organized into seven research programmes which all focus on different areas of cell and molecular biology: Computational Biology and Bioinformatics, Microbiology and Immunology, Molecular Biology, Molecular Biophysics, Molecular Evolution, Molecular Systems Biology and Structural Biology. The scientific basis of what we do lies in biology, but our research overlaps with other areas such as medicine, computer science, mathematics, chemistry, engineering sciences and physics. In total, we are over 200 staff and ~60 Ph.D. students. Please read more about the department’s work at https://icm.uu.se.

The position is placed in Kenta Okamoto’s research group at the Molecular Biophysics program. The research program focuses on single particle imaging of biomolecules using X-ray free electron laser and cryo-electron microscopy (cryo-EM), to reveal their functional 3D structures and the dynamics. In a part of our projects, we study structure-functions of pathogenic viruses that threaten our environment and health using cryo-EM and single particle analysis. The project will include developing time-resolved cryo-EM methods and the study of COVID-19 replication/transcribing intermediates. Please see our program homepage to find more details: https://www.icm.uu.se/molecular-biophysics

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Duties
The employee will be a part of the ongoing research projects supported by Swedish Research Council. As a research assistant within these projects you will support producing and purifying viruses/viral protein complexes for cryo-EM single particle analysis, and doing experiments using established approaches such as infectious clones of viruses.

Requirements
A Master of Science in natural sciences. You need to have an academic background in molecular biology focusing on viruses and the structures. You should also have experience on gene cloning and mutagenesis, protein and virus purifications, and quantitative PCR. The candidate should be able to work well as part of a team but also independently, and be proficient in both written and spoken English.

Additional qualifications
Experience in virus research using infectious cloning is considered an advantage.

About the employment
The employment is a temporary position, 6 months. Scope of employment 100 %. Starting date as agreed. Placement: Uppsala.

For further information about the position, please contact: Kenta Okamoto, 018-471 6691, kenta.okamoto@icm.uu.se.

Please submit your application by 29 June 2022, UFV-PA 2022/2487.

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Type of employment Special fixed-term employment
Contract type Full time
First day of employment 2022-08-01
Salary Individual salary
Number of positions 1
Full-time equivalent 100%
City Uppsala
County Uppsala län
Country Sweden
Reference number UFV-PA 2022/2487
Union representative
  • Seko Universitetsklubben, seko@uadm.uu.se
  • ST/TCO, tco@fackorg.uu.se
  • Saco-rådet, saco@uadm.uu.se
Published 15.Jun.2022
Last application date 29.Jun.2022 11:59 PM CEST

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