Uppsala University, Department of Medicinal Chemistry

The Department of Medicinal Chemistry at Uppsala University is a strong and international research environment. The department has about 85 employees and here, doctoral students, teachers, researchers and administrators work closely together in a creative and open environment. More information about the department can be found at: www.ilk.uu.se.

One postdoctoral position in Chemical Biology and Organic Chemistry for the Mass Spectrometric Discovery of Bioactive Microbiome Metabolites

Job Description: The position is available in the laboratory of Associate Professor Daniel Globisch at the Department of Medicinal Chemistry at Uppsala University in Sweden (https://www.ilk.uu.se/research-groups/biomarker-discovery/). The Globisch laboratory is an international and multidisciplinary research group with a focus on the development of new Chemical Biology methodologies to enhance the scope of quantitative and qualitative metabolomics-based research (Example literature: Angew. Chem. Int. Ed. 2018, 57, 13805-13809; Chem. Sci. 2018, 9, 6233-6239; Chem. Comm. 2019, 55, 9080-9083; check homepage for updates). The project will investigate microbiome-derived metabolites using chemoselective metabolite modification methods and mass spectrometric analysis. This project is co-funded by the laboratory of Associate Senior Lecturer Mikael Sellin (https://www.imbim.uu.se/research-groups/infection-and-defence/sellin-mikael/) for analysis of bacterial infections in intestinal organoid model systems. This highly interdisciplinary project will include techniques at the interface of Chemistry and Biology using a combination of Organic Chemistry, mass spectrometric analysis of metabolites, and microbiology. Our team is currently searching for a highly motivated postdoctoral researcher with passion and enthusiasm for science to support our interdisciplinary projects elucidating microbiome metabolism using mass spectrometry and the development of chemoselective probes.

Qualifications: The applicant must hold a PhD degree in chemical, biological or pharmaceutical sciences and should have expertise in at least three of the following areas: Chemical Biology, Organic Chemistry, Microbiology, and mass spectrometric analysis of metabolites. The PhD degree must have been received within three years at the time of employment.

Desirably/meritorious: Good written and spoken English skills and the ability to work in a team are required. Personal suitability will receive special attention in the selection process.

Work tasks: The selected candidate will perform chemical synthesis of chemoselective probes and metabolites, metabolite extraction, mass spectrometric analysis using UPLC-MS/MS techniques, and bacterial cultures. The postdoctoral position will be 100% research.

Application: The application, preferably written in English, should be submitted online and must include the following documents: 

  • Motivation letter with research interests and expertise as well as one paragraph on recent developments in mass spectrometric Chemical Biology or Microbiome research.
  • Curriculum Vitae with complete publication list
  • Copy of the PhD certificate
  • Contact information for at least two references

Salary: Individual salary.

Starting date: As soon as possible.

Type of employment: Temporary position according to central collective agreement.

Scope of employment: 100 % 

For further information about the research project please contact: Associate Professor Daniel Globisch, daniel.globisch@scilifelab.uu.se. 

For further information about the position please contact: Head of Dept Anders Karlén, anders.karlén@ilk.uu.se, 018-471 4293

Please submit your application by 3 July 2020, UFV-PA 2020/1800.

Are you considering moving to Sweden to work at Uppsala University? If so, you will find a lot of information about working and living in Sweden at www.uu.se/joinus. You are also welcome to contact International Faculty and Staff Services at ifss@uadm.uu.se.

Type of employment Temporary position
Contract type Full time
First day of employment Snarast
Salary Fast lön
Number of positions 1
Full-time equivalent 100
City Uppsala
County Uppsala län
Country Sweden
Reference number UFV-PA 2020/1800
Union representative
  • Seko Universitetsklubben, seko@uadm.uu.se
  • ST/TCO, tco@fackorg.uu.se
  • Saco-rådet, saco@uadm.uu.se
Published 14.May.2020
Last application date 03.Jul.2020 11:59 PM CEST

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