Uppsala University, Department of Cell and Molecular Biology

Uppsala University is a comprehensive research-intensive university with a strong international standing. Our mission is to pursue top-quality research and education and to interact constructively with society. Our most important assets are all the individuals whose curiosity and dedication make Uppsala University one of Sweden’s most exciting workplaces. Uppsala University has 46.000 students, 7.300 employees and a turnover of SEK 7.3 billion.

The Department of Cell and Molecular Biology is one of the most international, broad and distinguished molecular bioscience departments in Europe. The department comprises six research programs with about 130 employees. This PhD position will be within the Molecular Systems Biology program, in the research group of associate professor Sebastian Deindl.

The Deindl Lab offers a stimulating multidisciplinary environment where you will work closely with experts in biophysics, biochemistry, structural and molecular biology. Our overall mission is to investigate the molecular mechanisms of chromatin remodeling using a highly multidisciplinary approach that combines advanced single-molecule fluorescence imaging with a range of biophysical, structural, and biochemical techniques. For more information about the research in the Deindl laboratory, please visit http://www.deindl-lab.com/.

Work description: The student will investigate the activity and function of disease-related nucleosome-associated protein complexes. A strong focus will be on developing and applying novel single-molecule FRET-based imaging approaches to record the real-time dynamics with which the protein complexes manipulate nucleosomes. The student will additionally employ a range of biochemical approaches to characterize the nucleosome-interacting protein complexes. These efforts will greatly benefit from currently ongoing structural characterizations.
The doctoral student will primarily engage in his/her postgraduate education, other duties at the department may occur such as teaching and administrative work, but not more than 20% of the position.

Required qualifications: We are looking for a highly motivated candidate with a master's degree in physics, biophysics, biochemistry or similar. Excellent knowledge of English is a prerequisite, as the position is located in an international environment. We value personal characteristics such as good co-operative ability, a self-motivated personality, and a keen interest in basic research and in addressing fundamental biological questions with quantitative approaches.

Merits: Previous experience in wet-lab biochemistry as well as experience with optical microscopy are considered advantageous. Moreover, prior experience in programming and data analysis (e.g., using MatLab) is appreciated.  

The application: Your application is preferably written in English and must include the following:

  1. Your CV
  2. Copies of diplomas and certificates
  3. Contact information for two reference persons or recommendation letters from prior research supervisors.

Rules governing PhD students are set out in the Higher Education Ordinance chapter 5, §§ 1-7 and in Uppsala University's rules and guidelines http://regler.uu.se/?languageId=1.

Salary: According to local agreement for PhD students.

Starting date: As soon as posible or as otherwise agreed.

Type of employment: Temporary position according to the Higher Education Ordinance chapter 5 § 7.

Scope of employment: Full time 100 %

For further information about the position please contact: Martha Schattenhofer martha.schattenhofer@icm.uu.se. For administrative questions please contact HR--generalist Frida Österdahl frida.osterdahl@icm.uu.se

Please submit your application by April 17 2020, UFV-PA 2020/1147.

Are you considering moving to Sweden to work at Uppsala University? If so, you will find a lot of information about working and living in Sweden at www.uu.se/joinus. You are also welcome to contact International Faculty and Staff Services at ifss@uadm.uu.se.

Type of employment Temporary position longer than 6 months
Contract type Full time
First day of employment snarast
Salary Fixed salary
Number of positions 1
Working hours 100 %
City Uppsala
County Uppsala län
Country Sweden
Reference number UFV-PA 2020/1147
Union representative
  • Seko Universitetsklubben, seko@uadm.uu.se
  • ST/TCO, tco@fackorg.uu.se
  • Saco-rådet, saco@uadm.uu.se
Published 03.Apr.2020
Last application date 17.Apr.2020 11:59 PM CET

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