Uppsala University, Department of Medicinal Chemistry

The department of Medicinal Chemistry conducts research and teaching in the field of drug discovery. More information about the department and ongoing research and teaching is found at http://www.ilk.uu.se/. The department has a total of about 85 employees.

We are looking for postdoctor in Biomarker discovery in human samples using Organic Chemistry and Chemical Biology methodologies.

The position in Biomarker Discovery is available in the laboratory of Associate Professor Dr. Daniel Globisch at the Department of Medicinal Chemistry. The Globisch laboratory  is an international and multidisciplinary research group (http://www.ilk.uu.se/research-groups/biomarker-discovery) after recruitment by the Science For Life Laboratory (http://www.scilifelab.se/). Our research focus lies on the development of new methodologies to enhance the scope of quantitative and qualitative metabolomics-based research to simplify the discovery of disease-specific small molecule biomarkers in human samples (Example literature: Proc. Natl. Acad. Sci. U. S. A. 2013, 110, 4218-4223; Angew. Chem., Int. Ed. 2011, 50, 9739-9742, Bioorg. Med. Chem. Lett. 2017, 27, 3436-3440). Check our publication list for updates. The discovery of these specific early-stage biomarkers is crucial for the future development of disease diagnostics towards personalized treatment. We will utilize techniques at the interface of Chemistry and Biology with a combination of Chemical Biology techniques, Organic Chemistry, analysis of human samples, mass spectrometric analysis of metabolites, and investigation of metabolic pathways. Our team is currently searching for highly motivated and enthusiastic postdoctoral researcher with passion and enthusiasm for science to support our ongoing interdisciplinary research projects.

Duties:

The selected candidate will perform chemical synthesis of metabolites, metabolite extraction and mass spectrometric analysis of human samples, metabolomics analysis using UPLC-MS/MS techniques for biomarker discovery as well as enzymatic assays. The postdoctoral position will be 100% research.

Qualifications

The applicant must hold a PhD degree and should have expertise in at least three of the following areas: Chemical Biology, Biochemistry, Organic Chemistry, Metabolomics, and mass spectrometric analysis of human samples. Experience in chemical synthesis is preferred but not required. The PhD degree must have been received within three years at the time of employment. In special cases the PhD thesis may have been awarded earlier.

Desirably/meritorious

Good written and spoken English skills and the ability to work in a team are required. Personal suitability will receive special attention in the selection process.

Starting Date: The employment will start as soon as possible.

Employment Period: The period of employment is for two years.

Application: The application must be written in English, submitted online and include the following documents:

  1. Motivation letter with research interests and expertise as well as one paragraph on recent developments in Chemical Biology, Metabolomics or Biomarker Discovery.
  2. Curriculum Vitae with complete publication list
  3. Copy of the PhD certificate
  4. Contact information for at least two references

Salary: Individual salary

Starting date: As soon as possible

Type of employment: Temporary employment

Period of appointment: Two years

Level of employment: 100 %.

For further information about the position/research project/research area please contact:
Associate Professor Daniel Globisch (daniel.globisch@scilifelab.uu.se).

For further information about the employment please contact
Head of department Anders Karlén (anders.karlen@ilk.se)

You are welcome to submit your application through the online applications form no later than 2018-08-19, UFV-PA 2018/2364

Are you considering moving to Sweden to work at Uppsala University? If so, you will find much information about working and living in Sweden at www.uu.se/joinus. You are also welcome to contact the International Faculty and Staff Services at ifss@uadm.uu.se.

Type of employment Temporary position
Contract type Full time
Number of positions 1
Full-time equivalent 100%
City Uppsala
County Uppsala län
Country Sweden
Reference number UFV-PA 2018/2364
Union representative
  • Ellena Papaioannou, Seko, 018-471 3315
  • Suzanne Borén Andersson, TCO/ST, 018-471 6251
  • Per Sundman, Saco-rådet, 018-471 1485
Published 26.Jun.2018
Last application date 19.Aug.2018 11:59 PM CEST

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